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Ozempic Breath: Do Weight Loss Drugs Cause Bad Breath?

Ozempic and similar drugs like Wegovy, Monjouro, and Zepbound are revolutionizing weight loss for many people. In clinical trials, patients have seen significant reductions in body weight—about 15% with semaglutide-based drugs like Wegovy and Ozempic and even 21% with tripeptide-based drugs like Mounjaro and Zepbound. While these results are impressive, they do come with some side effects, primarily gastrointestinal discomfort. However, some less discussed but equally important side effects have emerged, including what’s being called “Ozempic breath.”

Dr. Neha Lalani explains that “Ozempic breath” is characterized by a fishy smell in burps or persistent bad breath. Although it’s not a widely recognized medical condition like other side effects, understanding its connection to gastrointestinal issues is important. Dr. Christopher McGowan, a gastroenterologist and obesity medicine specialist, stresses that while all medications have side effects, it’s essential to pinpoint the exact cause of bad breath to address it effectively. This attention to detail ensures that any side effects are managed as part of a comprehensive approach to health.

What Causes Ozempic Breath?

While bad breath isn’t officially listed as a side effect Ozempic, Monjouro, Zepbound, or Wegovy, there’s growing curiosity around what’s been dubbed “Ozempic breath.” Dr. Fatima Khan, a dentist and co-founder of Riven Oral Care, notes that there is ongoing research into this phenomenon. She highlights the importance of collecting long-term data to understand why some patients might experience oral hygiene issues, such as bad breath, while on these medications.

Interestingly, clinical trials have noted that burping, medically referred to as “eructation,” is a common side effect of these drugs. This could be a clue. Dr. Christopher McGowan explains that while foul-smelling breath directly from these medications hasn’t been conclusively proven, the act of belching could plausibly carry odors from the stomach into the mouth. This isn’t traditional bad breath but more of a stomach odor that escapes through the mouth, which can be quite potent. Patients have reported that these odors are strong enough to cause discomfort in social situations, leading to anxiety. This insight into how GLP-1 medications might affect oral health is crucial as it helps patients and healthcare providers manage potential side effects more effectively.

Why Does “Ozempic Burp” Happen?

Dr. Christopher McGowan explains why the infamous “Ozempic burp” occurs. He explains that it’s all tied to how GLP-1 medications like Ozempic work. These drugs slow down the rate at which the stomach empties, meaning food stays in your stomach much longer than usual. While this helps with eating less by making you feel fuller for a longer period, it has a downside.

Under normal conditions, the stomach is designed to clear out food within about four hours after a meal. However, with GLP-1 medications, food can linger in the stomach for much longer, sometimes even days. Over time, this food starts to break down and ferment, essentially turning the stomach into something like a compost bin. So, when you burp, you’re releasing some of those decomposing food odors, which can be quite unpleasant. This phenomenon is a straightforward, albeit sometimes socially awkward, side effect of how these medications help manage appetite.

He further explains that some patients might face additional challenges with GLP-1 medications like Ozempic. Side effects such as diarrhea & vomiting may lead to dehydration, which often causes dry mouth. Unfortunately, dry mouth is a well-known factor that can trigger bad breath. Moreover, while these medications effectively reduce hunger, they can significantly decrease food intake in rare instances. This drastic reduction can lead the body into a state called ketosis. 

This is a state where our body starts burning fat for energy instead of glucose. Ketosis can produce a sweet, acetone-like smell in the breath, which some might find unpleasant. To avoid this, he emphasizes the importance of Ozempic warnings and precautions, including maintaining a well-rounded diet with all the necessary macronutrients and ensuring the body receives the energy it needs without resorting to burning fat stores excessively.

Experiencing Oral Hygiene Issues While Taking Weight Loss Drugs

Dr. Fatima Khan points out that there are other oral health concerns to consider for those taking GLP-1 medications like Ozempic beyond just the unusual odors. Patients might notice several changes, including:

  • Acidic tastes linger in their mouth.
  • Enamel erosion, which means the hard, protective coating on the outside of your teeth wears away.
  • Increased tooth sensitivity, making eating hot or cold foods uncomfortable.
  • Gingivitis is an inflammation of the gums that can lead to more serious gum disease.
  • Tooth decay, where cavities can develop.

Dr. Khan also highlights that individuals with gastro-esophageal reflux disease (GERD) may face additional challenges. GERD often causes frequent heartburn and leaves a bitter, acidic taste in the mouth. Moreover, vomiting, which can occur as a side effect of these medications, contributes to enamel erosion. Protecting your enamel is crucial because it is the tough, mineralized outer layer that shields your teeth from daily wear and tear.

Dr. Fatima Khan explains that dental erosion happens when the enamel breaks down due to exposure to acidic substances. Conditions like GERD can make this erosion even worse. This erosion doesn’t just stop at surface-level damage; it can lead to a series of other dental issues. Patients might start noticing their teeth becoming more sensitive, changing color, or even appearing smaller than before.

Additionally, Dr. Khan points out that having a dry mouth, another possible side effect, significantly boosts the risk of tooth decay. It’s important to be extra vigilant with oral hygiene, especially since individuals with diabetes are already at a higher possibility of developing dental diseases.

How to Reduce Your Risk of “Ozempic Breath”?

While “Ozempic breath” and related symptoms can be bothersome, they typically improve as your body adjusts to the medication. In the meantime, he suggests some practical steps to help manage these issues. Basic oral hygiene practices like brushing daily & visiting your dentist at least two times a year are essential, no matter what medication you’re on.

Staying hydrated is especially important if you’re experiencing dry mouth, nausea, or vomiting, which are common side effects of these medications. Dr. McGowan also recommends eating a balanced diet to aid digestion and reduce issues. “Greasy, fatty foods take longer to digest and can increase belching and the odors that come with it,” he explains. Instead, opt for lean proteins, fruits, vegetables, and moderate amounts of healthy fats. Try to limit fast food, saturated fats, and greasy meats. Timing your meals can also make a difference. Dr. Neha Lalani suggests finishing your last meal at least three to four hours before going to bed. And if you’re still struggling with oral health issues despite these adjustments, it’s wise to consult with professionals even when you buy Ozempic from Canada.


While “Ozempic breath” isn’t officially recognized as a clinical condition, many people taking this medication do report experiencing unpleasant oral odors. This could be due to several reasons: burps that carry stomach odors (which isn’t technically bad breath), genuine halitosis, or ketosis—a condition where the body burns fat for energy, affecting breath smell. Additionally, side effects like nausea and vomiting from these medications can lead to dehydration, which in turn causes dry mouth, enamel erosion, tooth sensitivity, and discoloration.

Maintaining good oral hygiene by flossing & brushing regularly & visiting your dentist for routine check-ups may significantly help manage these side effects. Generally, these issues tend to resolve as your body adjusts to the medication over time. So, keeping up with these basic dental care practices is key to keeping your mouth healthy while on these treatments.

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